1. Department of Mathematics, Fu Jen Catholic University, New Taipei City 24205, Taiwan
2. Department of Biomedical Sciences, College of Medicine, Chang Gung University, Taoyuan 33302, Taiwan
3. Metabolomics Core Laboratory, Healthy Aging Research Center, Chang Gung University, Taoyuan 33302, Taiwan
4. Clinical Metabolomics Core Laboratory, Chang Gung Memorial Hospital, Taoyuan 33305, Taiwan
5. Institute of Statistical Science, Academia Sinica, Taipei 11529, Taiwan
6. Institute of Biomedical Sciences, Academia Sinica, Taipei 11529, Taiwan
7. Institute of Population Health Sciences, National Health Research Institutes, Miaoli 35053, Taiwan