Concentration-Dependent Enrichment Identifies Primary Protein Targets of Multitarget Bioactive Molecules-Reference-Cited by-同舟云学术

Concentration-Dependent Enrichment Identifies Primary Protein Targets of Multitarget Bioactive Molecules

Published:2023-01-30 Issue:3 Volume:22 Page:802-811
ISSN:1535-3893
Container-title:Journal of Proteome Research
language:en
Short-container-title:J. Proteome Res.

Author:

Xu Manyi¹,Ma Xingyu¹,Ye Zi¹,Wang Fengge¹,Xu Shiqi¹,Zhang Chong-Jing¹^ORCID

Affiliation:

1. State Key Laboratory of Bioactive Substance and Function of Natural Medicines and Beijing Key Laboratory of Active Substance Discovery and Druggability Evaluation, Institute of Materia Medica, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100050, China

Funder

Chinese Academy of Medical Sciences

National Natural Science Foundation of China

Publisher

American Chemical Society (ACS)

Subject

General Chemistry,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jproteome.2c00550

Reference30 articles.

1. A comprehensive map of molecular drug targets

2. Duocarmycin Analogues Target Aldehyde Dehydrogenase 1 in Lung Cancer Cells

3. Discovery of a Potent and Selective Covalent Inhibitor and Activity-Based Probe for the Deubiquitylating Enzyme UCHL1, with Antifibrotic Activity

4. Recent Progress in Structure-Based Evaluation of Compound Promiscuity

5. Compound promiscuity: what can we learn from current data?

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