Synthesis, Potency, and in Vivo Evaluation of 2-Piperazin-1-ylquinoline Analogues as Dual Serotonin Reuptake Inhibitors and Serotonin 5-HT1A Receptor Antagonists-Reference-Cited by-同舟云学术

Synthesis, Potency, and in Vivo Evaluation of 2-Piperazin-1-ylquinoline Analogues as Dual Serotonin Reuptake Inhibitors and Serotonin 5-HT1A Receptor Antagonists

Published:2009-07-21 Issue:15 Volume:52 Page:4955-4959
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Zhou Dahui¹,Stack Gary P.¹,Lo Jennifer¹,Failli Amedeo A.¹,Evrard Deborah A.¹,Harrison Boyd L.¹,Hatzenbuhler Nicole T.¹,Tran Megan¹,Croce Susan¹,Yi Soo¹,Golembieski Jeannette²,Hornby Geoffrey A.²,Lai Margaret²,Lin Qian²,Schechter Lee E.²,Smith Deborah L.²,Shilling Adam D.³,Huselton Christine³,Mitchell Paul⁴,Beyer Chad E.²,Andree Terrance H.²

Affiliation:

1. Chemical Sciences, Wyeth Research, CN 8000, Princeton, New Jersey 08543

2. Discovery Neurosciences, Wyeth Research, CN 8000, Princeton, New Jersey 08543

3. Drug Safety & Metabolism, Wyeth Research, 500 Arcola Road, Collegeville, Pennsylvania 19426

4. Department of Pharmacy and Pharmacology, University of Bath, Claverton Down, Bath BA2 7AY, U.K.

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm900374r

Reference22 articles.