1-Methylidenesqualene and 25-Methylidenesqualene as Active-Site Probes for Bacterial Squalene:Hopene Cyclase
Author:
Affiliation:
1. University of Shizuoka, School of Pharmaceutical Sciences, and the 21st Century COE Program, 52-1 Yada, Shizuoka 422-8526, Japan
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/ol036509r
Reference14 articles.
1. Structural Basis for Cyclic Terpene Biosynthesis by Tobacco 5-Epi-Aristolochene Synthase
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1. Squalene-Hopene Cyclase: Mechanistic Insights into the Polycyclization Cascades of Squalene Analogs Bearing Ethyl and Hydroxymethyl Groups at the C-2 and C-23 Positions;Chemistry - A European Journal;2018-07-05
2. Mutated variants of squalene-hopene cyclase: enzymatic syntheses of triterpenes bearing oxygen-bridged monocycles and a new 6,6,6,6,6-fusded pentacyclic scaffold, named neogammacerane, from 2,3-oxidosqualene;Organic & Biomolecular Chemistry;2018
3. Enzymatic Addition of Alcohols to Terpenes by Squalene Hopene Cyclase Variants;ChemBioChem;2017-10-02
4. β-Amyrin biosynthesis: catalytic mechanism and substrate recognition;Organic & Biomolecular Chemistry;2017
5. Squalene-hopene cyclases—evolution, dynamics and catalytic scope;Current Opinion in Structural Biology;2016-12
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