A Mechanistic Hypothesis for the Aspirin-Induced Switch in Lipid Mediator Production by Cyclooxygenase-2
Author:
Affiliation:
1. Department of Drug Science and Technology, Via Pietro Giuria 9, 10125 Torino, Italy
Publisher
American Chemical Society (ACS)
Subject
Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis
Link
https://pubs.acs.org/doi/pdf/10.1021/ja402870k
Reference23 articles.
1. Cyclooxygenases: Structural, Cellular, and Molecular Biology
2. Cyclooxygenase Enzymes: Regulation and Function
3. The COXIB Experience: A Look in the Rearview Mirror
4. Control of Oxygenation in Lipoxygenase and Cyclooxygenase Catalysis
5. Different Catalytically Competent Arrangements of Arachidonic Acid within the Cyclooxygenase Active Site of Prostaglandin Endoperoxide H Synthase-1 Lead to the Formation of Different Oxygenated Products
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