Novel Class of LIM-Kinase 2 Inhibitors for the Treatment of Ocular Hypertension and Associated Glaucoma-Reference-Cited by-同舟云学术

Novel Class of LIM-Kinase 2 Inhibitors for the Treatment of Ocular Hypertension and Associated Glaucoma

Published:2009-10-15 Issue:21 Volume:52 Page:6515-6518
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Harrison Bryce A.¹,Whitlock N. Andrew²,Voronkov Michael V.¹,Almstead Zheng Y.¹,Gu Kun-jian¹,Mabon Ross¹,Gardyan Michael¹,Hamman Brian D.³,Allen Jason³,Gopinathan Suma⁴,McKnight Beth²,Crist Mike²,Zhang Yulian¹,Liu Ying¹,Courtney Lawrence F.¹,Key Billie³,Zhou Julia³,Patel Nita³,Yates Phil W.⁵,Liu Qingyun³,Wilson Alan G. E.⁴,Kimball S. David¹,Crosson Craig E.⁵,Rice Dennis S.²,Rawlins David B.¹

Affiliation:

1. Department of Medicinal Chemistry, Lexicon Pharmaceuticals, 350 Carter Road, Princeton, New Jersey 08540

2. Department of Ophthalmology

3. Department of Pharmaceutical Discovery

4. Department of Drug Metabolism, Pharmacokinetics, and Toxicology

5. Department of Ophthalmology, Medical University of South Carolina, 167 Ashley Avenue, Charleston, South Carolina 29425

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm901226j