Development and Scale-Up of Three Consecutive Continuous Reactions for Production of 6-Hydroxybuspirone
Author:
Affiliation:
1. Bristol-Myers Squibb, Process Research and Development, One Squibb Drive, New Brunswick, New Jersey 08903, U.S.A.
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Physical and Theoretical Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/op800079u
Reference14 articles.
1. Development of a Safe and Scalable Oxidation Process for the Preparation of 6-Hydroxybuspirone: Application of In-Line Monitoring for Process Ruggedness and Product Quality
2. Development of a Continuous Process for the Industrial Generation of Diazomethane1
3. Reaction Engineering Evaluation and Utilization of Static Mixer Technology for the Synthesis of Pharmaceuticals
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