Development of a Safe and Scalable Oxidation Process for the Preparation of 6-Hydroxybuspirone: Application of In-Line Monitoring for Process Ruggedness and Product Quality-Reference-Cited by-同舟云学术

Development of a Safe and Scalable Oxidation Process for the Preparation of 6-Hydroxybuspirone: Application of In-Line Monitoring for Process Ruggedness and Product Quality

Published:2004-06-12 Issue:4 Volume:8 Page:616-623
ISSN:1083-6160
Container-title:Organic Process Research & Development
language:en
Short-container-title:Org. Process Res. Dev.

Author:

Watson Daniel J.¹,Dowdy Eric D.¹,DePue Jeffrey S.¹,Kotnis Atul S.¹,Leung Simon¹,O'Reilly Brian C.¹

Affiliation:

1. Bristol-Myers Squibb Pharmaceutical Research Institute, Department of Process Research and Development, One Squibb Drive, New Brunswick, New Jersey 08903

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/op049918r

Reference8 articles.

1. Mayol, R. F. U.S. Patent 2000/6150365.

2. (a) Yevich, J. P.; Mayol, R. F.; Li, J.; Ruediger, E. H. US Patent 2003/0069251 A1.

3. (b) Yevich, J. P.; Mayol, R. F.; Li, J.; Yocca, F. WO 03/009851 A1; (c) Yevich, J. P.; Mayol, R. F.; Li, J.; Yocca, F. U.S. Patent 2003/0022899 A1.

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