Antimalarial Dual Drugs Based on Potent Inhibitors of Glutathione Reductase from Plasmodium falciparum-Reference-Cited by-同舟云学术

Antimalarial Dual Drugs Based on Potent Inhibitors of Glutathione Reductase from Plasmodium falciparum

Published:2008-02-09 Issue:5 Volume:51 Page:1260-1277
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Friebolin Wolfgang¹,Jannack Beate¹,Wenzel Nicole¹,Furrer Julien¹,Oeser Thomas¹,Sanchez Cecilia P.¹,Lanzer Michael¹,Yardley Vanessa¹,Becker Katja¹,Davioud-Charvet Elisabeth¹

Affiliation:

1. Biochemie-Zentrum der Universität Heidelberg, Im Neuenheimer Feld 504, 69120 Heidelberg, Germany, Organisch-Chemisches Institut der Universität Heidelberg, Im Neuenheimer Feld 270, 69120 Heidelberg, Germany, Hygiene Institut, Abt. Parasitologie, Im Neuenheimer Feld 324, 69120 Heidelberg, Department of Infections and Tropical Diseases, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, U.K., Interdisciplinary Research Center, Justus-Liebig-University, Heinrich-Buff-Ring 26-32,...

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm7009292

Reference91 articles.

1. Ferriprotoporphyrin IX Fulfills the Criteria for Identification as the Chloroquine Receptor of Malaria Parasites.

2. Identification of the acidic compartment of Plasmodium falciparum-infected human erythrocytes as the target of the antimalarial drug chloroquine.

3. An Assessment of Drug-Haematin Binding as a Mechanism for Inhibition of Haematin Polymerisation by Quinoline Antimalarials

4. Solution Structures of Antimalarial Drug−Heme Complexes

5. NMR Studies of Chloroquine−Ferriprotoporphyrin IX Complex

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