The Design and Synthesis of Potent and Selective Inhibitors of Trypanosoma brucei Glycogen Synthase Kinase 3 for the Treatment of Human African Trypanosomiasis-Reference-Cited by-同舟云学术

The Design and Synthesis of Potent and Selective Inhibitors of Trypanosoma brucei Glycogen Synthase Kinase 3 for the Treatment of Human African Trypanosomiasis

Published:2014-09-08 Issue:18 Volume:57 Page:7536-7549
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Urich Robert¹,Grimaldi Raffaella¹,Luksch Torsten¹,Frearson Julie A.¹,Brenk Ruth²,Wyatt Paul G.¹

Affiliation:

1. Drug Discovery Unit, College of Life Sciences, University of Dundee, Sir James Black Centre, Dow Street, Dundee DD1 5EH, U.K.

2. Division of Biological Chemistry and Drug Discovery, College of Life Sciences, University of Dundee, Sir James Black Centre, Dundee DD1 5EH, U.K.

Funder

Wellcome Trust

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm500239b

Reference33 articles.

1. Opportunities and Challenges in Antiparasitic Drug Discovery

2. Synthesis and Evaluation of Indatraline-Based Inhibitors for Trypanothione Reductase

3. Chemotherapy of human African trypanosomiasis: current and future prospects

4. High-throughput decoding of antitrypanosomal drug efficacy and resistance

5. Inhibitors of casein kinase 1 block the growth of Leishmania major promastigotes in vitro

Cited by 30 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Multi-targeted anti-Alzheimer's agents: Synthesis, biological evaluation, and molecular modeling study of some pyrazolopyridine hybrids;European Journal of Medicinal Chemistry;2023-12

2. Targeted protein degradation might present a novel therapeutic approach in the fight against African trypanosomiasis;European Journal of Pharmaceutical Sciences;2023-07

3. Piplartine-Inspired 3,4,5-Trimethoxycinnamates: Trypanocidal, Mechanism of Action, and In Silico Evaluation;Molecules;2023-06-02

4. The critical role of mode of action studies in kinetoplastid drug discovery;Frontiers in Drug Discovery;2023-05-10

5. Synthesis and evaluation of tetrahydroisoquinoline derivatives against Trypanosoma brucei rhodesiense;European Journal of Medicinal Chemistry;2021-12