Synthesis and Evaluation of Indatraline-Based Inhibitors for Trypanothione Reductase-Reference-Cited by-同舟云学术

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Synthesis and Evaluation of Indatraline-Based Inhibitors for Trypanothione Reductase

Published:2010-12-15 Issue:2 Volume:6 Page:321-328
ISSN:1860-7179
Container-title:ChemMedChem
language:en
Short-container-title:ChemMedChem

Author:

Walton Jeffrey G. A.,Jones Deuan C.,Kiuru Paula,Durie Alastair J.,Westwood Nicholas J.,Fairlamb Alan H.

Publisher

Wiley

Subject

Organic Chemistry,General Pharmacology, Toxicology and Pharmaceutics,Molecular Medicine,Drug Discovery,Biochemistry,Pharmacology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/cmdc.201000442/fullpdf

Reference30 articles.

1. Kinetoplastids: related protozoan pathogens, different diseases

2. Trypanothione: A Novel Bis(glutathionyl)spermidine Cofactor for Glutathione Reductase in Trypanosomatids

3. METABOLISM AND FUNCTIONS OF TRYPANOTHIONE IN THE KINETOPLASTIDA

4. Substrate interactions between trypanothione reductase and N1-glutathionylspermidine disulphide at 0.28-nm resolution

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