Formal Synthesis of (−)-Perhydrohistrionicotoxin via Cyclic Amino Acid Ester−Enolate Claisen Rearrangement and Ring-Closing Metathesis
Author:
Affiliation:
1. College of Pharmacy, Seoul National University, San 56-1, Shilim, Kwanak, Seoul 151-742, Korea, and Natural Products Research Institute, College of Pharmacy, Seoul National University, 28 Yungun, Jongro, Seoul 110-460, Korea pennkim@snu.ac.kr
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/jo050608w
Reference28 articles.
1. Histrionicotoxins: Roentgen-Ray Analysis of the Novel Allenic and Acetylenic Spiroalkaloids Isolated from a Colombian Frog, Dendrobates histrionicus
2. Thirty Years of Discovering Arthropod Alkaloids in Amphibian Skin
3. A Two-Directional Synthesis of (±)-Perhydrohistrionicotoxin
4. Combining the [2,3] sigmatropic rearrangement and ring-closing metathesis strategies for the synthesis of spirocyclic alkaloids. A short and efficient route to (±)-perhydrohistrionicotoxin
5. Simple total synthesis of (+-)-perhydrohistrionicotoxin
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