An HIV RNase H Inhibitory 1,3,4,5-Tetragalloylapiitol from the African Plant Hylodendron gabunensis
Author:
Affiliation:
1. Molecular Targets Development Program, Center for Cancer Research, National Cancer Institute, Building 1052, Room 121, Frederick, Maryland 21702-1201
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Complementary and alternative medicine,Drug Discovery,Pharmaceutical Science,Pharmacology,Molecular Medicine,Analytical Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/np0702279
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1. Crystal Structure at 3.5 Å Resolution of HIV-1 Reverse Transcriptase Complexed with an Inhibitor
2. Structure of HIV-1 reverse transcriptase/DNA complex at 7 Å resolution showing active site locations
3. Crystal structure of human immunodeficiency virus type 1 reverse transcriptase complexed with double-stranded DNA at 3.0 A resolution shows bent DNA.
4. RNase H activity associated with bacterially expressed reverse transcriptase of human T-cell lymphotropic virus III/lymphadenopathy-associated virus.
5. Mutations within the RNase H Domain of Human Immunodeficiency Virus Type 1 Reverse Transcriptase Abolish Virus Infectivity
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