Determination of the α-Conotoxin Vc1.1 Binding Site on the α9α10 Nicotinic Acetylcholine Receptor-Reference-Cited by-同舟云学术

Determination of the α-Conotoxin Vc1.1 Binding Site on the α9α10 Nicotinic Acetylcholine Receptor

Published:2013-04-29 Issue:9 Volume:56 Page:3557-3567
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Yu Rilei¹,Kompella Shiva N.²,Adams David J.²,Craik David J.¹,Kaas Quentin¹

Affiliation:

1. Division of Chemistry and Structural Biology, Institute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland 4072, Australia

2. Health Innovations Research Institute, RMIT University, Melbourne, Victoria 3083, Australia

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm400041h

Reference47 articles.

1. A Novel α-Conotoxin Identified by Gene Sequencing Is Active in Suppressing the Vascular Response to Selective Stimulation of Sensory Nerves in Vivo

2. Therapeutic applications of conotoxins that target the neuronal nicotinic acetylcholine receptor

3. Engineering of Conotoxins for the Treatment of Pain

4. The Engineering of an Orally Active Conotoxin for the Treatment of Neuropathic Pain

5. Molecular mechanism for analgesia involving specific antagonism of 9 10 nicotinic acetylcholine receptors

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