Peptide Truncation Leads to a Twist and an Unusual Increase in Affinity for Casitas B-Lineage Lymphoma Tyrosine Kinase Binding Domain-Reference-Cited by-同舟云学术

Peptide Truncation Leads to a Twist and an Unusual Increase in Affinity for Casitas B-Lineage Lymphoma Tyrosine Kinase Binding Domain

Published:2012-03-19 Issue:7 Volume:55 Page:3583-3587
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Kumar Eric A.¹,Yuan Ziyan¹,Palermo Nicholas Y.,Dong Lin,Ahmad Gulzar,Lokesh G. L.¹,Kolar Carol,Kizhake Smitha¹,Borgstahl Gloria E. O.,Band Hamid,Natarajan Amarnath¹

Affiliation:

1. Chemical Biology Program, Department of Pharmacology, University of Texas Medical Branch, Galveston, Texas 77555, United States

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm300078z

Reference32 articles.

1. Ubiquitin in trafficking: The network at work

2. The Cbl Family and Other Ubiquitin Ligases

3. The Tyrosine Kinase Negative Regulator c-Cbl as a RING-Type, E2-Dependent Ubiquitin-Protein Ligase

4. Ubiquitin Ligase Activity and Tyrosine Phosphorylation Underlie Suppression of Growth Factor Signaling by c-Cbl/Sli-1

5. A Conserved DpYR Motif in the Juxtamembrane Domain of the Met Receptor Family Forms an Atypical c-Cbl/Cbl-b Tyrosine Kinase Binding Domain Binding Site Required for Suppression of Oncogenic Activation

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