1. Key Laboratory of Regenerative Biology, Guangzhou Institute of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, Guangdong, China 510663, Department of Chemistry and Molecular Biology, North Dakota State University, Fargo, North Dakota 58105, and Center for Research at Bio/Nano Interface, Department of Chemistry, Shands Cancer Center, Department of Physiology and Functional Genomics, UF Genetics Institute and McKnight Brain Institute, University of Florida, Gainesville, Florida 32611-7200