Synthesis of the Branched C-Glycoside Substructure of Altromycin B
Author:
Affiliation:
1. Department of Chemistry, Emory University, Atlanta, Georgia 30322
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/ol050975u
Reference32 articles.
1. Altromycins, novel pluramycin-like antibiotics. I. Taxonomy of the producing organism, fermentation and antibacterial activity.
2. Altromycins, novel pluramycin-like antibiotics. II. Isolation and elucidation of structure.
3. Altromycin B Threads the DNA Helix Interacting with Both the Major and the Minor Grooves To Position Itself for Site-Directed Alkylation and Guanine N7
4. Hedamycin intercalates the DNA helix and, through carbohydrate-mediated recognition in the minor groove, directs N7-alkylation of guanine in the major groove in a sequence-specific manner
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