The Marine Sponge Diacarnus bismarckensis as a Source of Peroxiterpene Inhibitors of Trypanosoma brucei, the Causative Agent of Sleeping Sickness-Reference-Cited by-同舟云学术

The Marine Sponge Diacarnus bismarckensis as a Source of Peroxiterpene Inhibitors of Trypanosoma brucei, the Causative Agent of Sleeping Sickness

Published:2009-01-21 Issue:2 Volume:72 Page:218-222
ISSN:0163-3864
Container-title:Journal of Natural Products
language:en
Short-container-title:J. Nat. Prod.

Author:

Rubio Brent K.¹,Tenney Karen¹,Ang Kean-Hooi¹,Abdulla Maha¹,Arkin Michelle¹,McKerrow James H.¹,Crews Phillip¹

Affiliation:

1. Department of Chemistry and Biochemistry and Institute for Marine Sciences, University of California Santa Cruz, Santa Cruz, California 95064, Sandler Center for Basic Research in Parasitic Disease, University of California San Francisco, San Francisco, California 94143, and Small Molecule Discovery Center, University of California San Francisco, San Francisco, California 94158

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Complementary and alternative medicine,Drug Discovery,Pharmaceutical Science,Pharmacology,Molecular Medicine,Analytical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/np800711a

Reference35 articles.

1. World Health Organization: Human African Trypanosomiasis.http://www.who.int/trypanosomiasis_african/en/index.html(Sept 12, 2008).

2. Development of Potent Purine-Derived Nitrile Inhibitors of the Trypanosomal Protease TbcatB

3. The continuing problem of human African trypanosomiasis (sleeping sickness)

4. Human African trypanosomiasis: pharmacological re-engagement with a neglected disease

5. Discovery of trypanocidal thiosemicarbazone inhibitors of rhodesain and TbcatB

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