Design, Synthesis, and Biological Activity of a Potent Inhibitor of the Neuropeptidase N-Acetylated α-Linked Acidic Dipeptidase
Author:
Affiliation:
1. Departments of Medicinal Chemistry and Pharmacology, ZENECA Pharmaceuticals, Wilmington, Delaware 19897
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/jm950801q
Reference21 articles.
1. An explanation for the purported excitation of piriform cortical neurons by N-acetyl-L-aspartyl-L-glutamic acid (NAAG).
2. N-acetyl-aspartylglutamate (NAAG) elicits rapid increase in intraneuronal Ca2+ in vitro
3. Genetically epilepsy-prone rats have increased brain regional activity of an enzyme which liberates glutamate from N-acetyl-aspartyl-glutamate
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