Profiling the Structural Determinants for the Selectivity of Representative Factor-Xa and Thrombin Inhibitors Using Combined Ligand-Based and Structure-Based Approaches-Reference-Cited by-同舟云学术

Profiling the Structural Determinants for the Selectivity of Representative Factor-Xa and Thrombin Inhibitors Using Combined Ligand-Based and Structure-Based Approaches

Published:2011-08-01 Issue:8 Volume:51 Page:1966-1985
ISSN:1549-9596
Container-title:Journal of Chemical Information and Modeling
language:en
Short-container-title:J. Chem. Inf. Model.

Author:

Bhunia Shome S.¹,Roy Kuldeep K.¹,Saxena Anil K.¹

Affiliation:

1. Division of Medicinal and Process Chemistry, Central Drug Research Institute, CSIR, Lucknow, India - 226001

Publisher

American Chemical Society (ACS)

Subject

Library and Information Sciences,Computer Science Applications,General Chemical Engineering,General Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/ci200185q

Reference49 articles.

1. Factor Xa Inhibitors: Next-Generation Antithrombotic Agents

2. New Antithrombotic Drugs

3. New anticoagulants – towards the development of an "ideal" anticoagulant

4. Factor Xa or thrombin: is factor Xa a better target?

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