Nonenzymatic Oxidative Steps Accompanying Action of the Cytochrome P450 Enzymes StaP and RebP in the Biosynthesis of Staurosporine and Rebeccamycin
Author:
Affiliation:
1. Department of Biological Chemistry & Molecular Pharmacology, Harvard Medical School, 240 Longwood Avenue, Boston, Massachusetts 02115
Publisher
American Chemical Society (ACS)
Subject
Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis
Link
https://pubs.acs.org/doi/pdf/10.1021/ja0743801
Reference14 articles.
1. The Biosynthetic Gene Cluster for the Antitumor Rebeccamycin
2. Characterization of the Biosynthetic Gene Cluster of Rebeccamycin fromLechevalieria aerocolonigenesATCC 39243
3. Cloning of the Staurosporine Biosynthetic Gene Cluster from Streptomyces sp. TP-A0274 and Its Heterologous Expression in Streptomyces lividans.
4. Biosynthesis of Hexahydroxyperylenequinone Melanin via Oxidative Aryl Coupling by Cytochrome P-450 in Streptomyces griseus
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