Discovery of 1,3-Diaminobenzenes as Selective Inhibitors of Platelet Activation at the PAR1 Receptor-Reference-Cited by-同舟云学术

Discovery of 1,3-Diaminobenzenes as Selective Inhibitors of Platelet Activation at the PAR1 Receptor

Published:2012-01-30 Issue:3 Volume:3 Page:232-237
ISSN:1948-5875
Container-title:ACS Medicinal Chemistry Letters
language:en
Short-container-title:ACS Med. Chem. Lett.

Author:

Dockendorff Chris¹,Aisiku Omozuanvbo²,VerPlank Lynn¹,Dilks James R.²,Smith Daniel A.²,Gunnink Susanna F.²,Dowal Louisa²,Negri Joseph¹,Palmer Michelle¹,MacPherson Lawrence¹,Schreiber Stuart L.¹³,Flaumenhaft Robert²

Affiliation:

1. Chemical Biology Platform and Probe Development Center, Broad Institute of Harvard and MIT, 7 Cambridge Center, Cambridge, Massachusetts 02142, United States

2. Division of Hemostasis and Thrombosis, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02215, United States

3. Howard Hughes Medical Institute, Broad Institute of Harvard and MIT, 7 Cambridge Center, Cambridge, Massachusetts 02142, United States

Funder

American Heart Association

National Institutes of Health

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/ml2002696

Reference25 articles.

1. Antiplatelet therapies for the treatment of cardiovascular disease