Baicalein Protects against 6-OHDA-Induced Neurotoxicity through Activation of Keap1/Nrf2/HO-1 and Involving PKCα and PI3K/AKT Signaling Pathways

Author:

Zhang Zaijun123,Cui Wei4,Li Guohui5,Yuan Shuai12,Xu Daping12,Hoi Maggie P.M.12,Lin Zhixiu6,Dou Juan78,Han Yifan4,Lee Simon M.Y.12

Affiliation:

1. State Key Laboratory of Quality Research in Chinese Medicine (University of Macau), Macao SAR, China

2. Institute of Chinese Medical Sciences, University of Macau, Macao SAR, China

3. Institute of New Drug Research, Guangdong Province Key Laboratory of Pharmacodynamic, Constituents of Traditional Chinese Medicine & New Drug Research, College of Pharmacy, Jinan University, Guangdong, China

4. Department of Applied Biology and Chemical Technology, Institute of Modern Medicine, The Hong Kong Polytechnic University, Hong Kong SAR, China

5. Department of Chemistry, Hong Kong University, Hong Kong SAR, China

6. School of Chinese Medicine, The Chinese University of Hong Kong, Hong Kong SAR, China

7. Department of Pediatrics, The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China

8. Departments of Pharmacology and Neurology, Emory University School of Medicine, Atlanta, Georgia 30322, United States

Publisher

American Chemical Society (ACS)

Subject

General Agricultural and Biological Sciences,General Chemistry

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