Enantioselective Synthesis of a Highly Substituted Tetrahydrofluorene Derivative as a Potent and Selective Estrogen Receptor Beta Agonist-Reference-Cited by-同舟云学术

Enantioselective Synthesis of a Highly Substituted Tetrahydrofluorene Derivative as a Potent and Selective Estrogen Receptor Beta Agonist

Published:2014-03-13 Issue:4 Volume:18 Page:528-538
ISSN:1083-6160
Container-title:Organic Process Research & Development
language:en
Short-container-title:Org. Process Res. Dev.

Author:

Maddess Matthew L.¹,Scott Jeremy P.²,Alorati Anthony²,Baxter Carl²,Bremeyer Nadine²,Brewer Sarah²,Campos Kevin¹,Cleator Ed²,Dieguez-Vazquez Alejandro²,Gibb Andrew²,Gibson Andrew²,Howard Melissa¹,Keen Stephen²,Klapars Artis¹,Lee Jaemoon¹,Li Jing¹,Lynch Joseph¹,Mullens Peter²,Wallace Debra¹,Wilson Robert²

Affiliation:

1. Global Process Chemistry, Merck & Co., Inc., PO Box 2000, Rahway, New Jersey 07065-0900, United States

2. Global Process Chemistry, Merck Sharp & Dohme Research Laboratories, Hertford Road, Hoddesdon, Hertfordshire EN11 9BU, U.K.

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/op5000489

Reference38 articles.

1. Hormone replacement therapy

2. Hormonal Treatment of Postmenopausal Women

3. Hormone replacement therapy: controversies, pros and cons

4. Effects of Conjugated Equine Estrogen in Postmenopausal Women With Hysterectomy

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