Membrane-Induced pKa Shifts in wt-pHLIP and Its L16H Variant-Reference-Cited by-同舟云学术

Membrane-Induced pKa Shifts in wt-pHLIP and Its L16H Variant

Published:2018-05-07 Issue:6 Volume:14 Page:3289-3297
ISSN:1549-9618
Container-title:Journal of Chemical Theory and Computation
language:en
Short-container-title:J. Chem. Theory Comput.

Author:

Vila-Viçosa Diogo¹,Silva Tomás F. D.¹,Slaybaugh Gregory²,Reshetnyak Yana K.²,Andreev Oleg A.²,Machuqueiro Miguel¹^ORCID

Affiliation:

1. Centro de Química e Bioquímica, BioISI: Biosystems and Integrative Sciences Institute, Departamento de Química e Bioquímica, Faculdade de Ciências, Universidade de Lisboa, 1749-016 Lisboa, Portugal

2. Department of Physics, University of Rhode Island, 2 Lippitt Road, Kingston, Rhode Island 02881, United States

Funder

National Institute of General Medical Sciences

Funda??o para a Ci?ncia e a Tecnologia

Publisher

American Chemical Society (ACS)

Subject

Physical and Theoretical Chemistry,Computer Science Applications

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jctc.8b00102

Reference70 articles.

1. Spontaneous, pH-Dependent Membrane Insertion of a Transbilayer α-Helix

2. Translocation of molecules into cells by pH-dependent insertion of a transmembrane helix

3. A Monomeric Membrane Peptide that Lives in Three Worlds: In Solution, Attached to, and Inserted across Lipid Bilayers

4. pHLIP peptide targets nanogold particles to tumors

5. Targeting diseased tissues by pHLIP insertion at low cell surface pH

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