Fine-Tuning and Enhancement of pH-Dependent Membrane Permeation of Cyclic Peptides by Utilizing Noncanonical Amino Acids with Extended Side Chains-Reference-Cited by-同舟云学术

Fine-Tuning and Enhancement of pH-Dependent Membrane Permeation of Cyclic Peptides by Utilizing Noncanonical Amino Acids with Extended Side Chains

Published:2023-05-15 Issue:10 Volume:66 Page:7054-7062
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Matsuda Motomi¹,Ikeda Keisuke¹^ORCID,Kameda Tomoshi²^ORCID,Nakao Hiroyuki¹^ORCID,Nakano Minoru¹^ORCID

Affiliation:

1. Department of Biointerface Chemistry, Faculty of Pharmaceutical Sciences, University of Toyama, Sugitani 2630, Toyama 930-0194, Japan

2. Artificial Intelligence Research Center, National Institute of Advanced Industrial Science and Technology (AIST), 2-4-7 Aomi, Koto-ku, Tokyo 135-0064, Japan

Funder

Japan Society for the Promotion of Science

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.3c00628

Reference40 articles.

1. Cell-Penetrating Peptides: Design, Synthesis, and Applications

2. Cell-penetrating peptides: A tool for effective delivery in gene-targeted therapies

3. Nanoparticles Modified with Cell-Penetrating Peptides: Conjugation Mechanisms, Physicochemical Properties, and Application in Cancer Diagnosis and Therapy

4. Delivery of antibodies to the cytosol

5. Cell-penetrating peptide sequence and modification dependent uptake and subcellular distribution of green florescent protein in different cell lines

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