Rational Design, Synthesis, and Biological Activity of Novel Conformationally Restricted Vitamin D Analogues, (22R)- and (22S)-22-Ethyl-1,25-dihydroxy-23,24-didehydro-24a,24b-dihomo-20-epivitamin D3

Author:

Masuno Hiroyuki1,Yamamoto Keiko1,Wang Xinxiang1,Choi Mihwa1,Ooizumi Hiroshi1,Shinki Toshimasa1,Yamada Sachiko1

Affiliation:

1. Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University, 2-3-10, Kanda-Surugadai, Chiyoda-ku, Tokyo 101-0062, Japan, Department of Genetics and Molecular Biology, Kyoto University, Kyoto 606-8507, Japan, and School of Dentistry, Showa University, Tokyo 142-8555, Japan

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

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