Computational Predictions of Binding Affinities to Dihydrofolate Reductase: Synthesis and Biological Evaluation of Methotrexate Analogues-Reference-Cited by-同舟云学术

Computational Predictions of Binding Affinities to Dihydrofolate Reductase: Synthesis and Biological Evaluation of Methotrexate Analogues

Published:2000-10-01 Issue:21 Volume:43 Page:3852-3861
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Graffner-Nordberg Malin¹,Marelius John¹,Ohlsson Sofie¹,Persson Åsa¹,Swedberg Göte¹,Andersson Paul¹,Andersson Sven E.¹,Åqvist Johan¹,Hallberg Anders¹

Affiliation:

1. Department of Organic Pharmaceutical Chemistry, Uppsala Biomedical Center, Uppsala University, Box 574, SE-751 23 Uppsala, Sweden; Department of Cell and Molecular Biology, Uppsala Biomedical Center, Uppsala University, Box 596, SE-751 24 Uppsala, Sweden; Discovery, AstraZeneca R&D Lund, SE-221 87 Lund, Sweden; Department of Pharmaceutical Microbiology, Uppsala Biomedical Center, Uppsala University, Box 581, SE-751 23 Uppsala, Sweden; and Department of Internal Medicine, Lund University Hospital, SE-221...

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm0009639

Reference46 articles.

1. Weekly Pulse Methotrexate in Rheumatoid Arthritis

2. Efficacy of Low-Dose Methotrexate in Rheumatoid Arthritis

3. Parenteral Methotrexate in Psoriasis

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