Total Synthesis and Pharmacological Characterization of Solomonsterol A, a Potent Marine Pregnane-X-Receptor Agonist Endowed with Anti-Inflammatory Activity-Reference-Cited by-同舟云学术

Total Synthesis and Pharmacological Characterization of Solomonsterol A, a Potent Marine Pregnane-X-Receptor Agonist Endowed with Anti-Inflammatory Activity

Published:2011-06-03 Issue:13 Volume:54 Page:4590-4599
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Sepe Valentina¹,Ummarino Raffaella¹,D’Auria Maria Valeria¹,Mencarelli Andrea²,D’Amore Claudio²,Renga Barbara²,Zampella Angela¹,Fiorucci Stefano²

Affiliation:

1. Dipartimento di Chimica delle Sostanze Naturali, Università di Napoli “Federico II”, via D. Montesano 49, 80131 Napoli, Italy

2. Dipartimento di Medicina Clinica e Sperimentale, Università di Perugia, Nuova Facoltà di Medicina e Chirurgia, Via Gerardo Dottori 1, S. Andrea delle Fratte, 06132 Perugia, Italy

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm200241s

Reference36 articles.

1. Role of mucosal dendritic cells in inflammatory bowel disease

2. Mucosal T Cell Proliferation and Apoptosis in Inflammatory Bowel Disease

3. Anatomical Profiling of Nuclear Receptor Expression Reveals a Hierarchical Transcriptional Network

4. The Sterile Inflammatory Response

5. Rifaximin Is a Gut-Specific Human Pregnane X Receptor Activator

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