Detection and Structural Characterization of Glutathione-Trapped Reactive Metabolites Using Liquid Chromatography−High-Resolution Mass Spectrometry and Mass Defect Filtering-Reference-Cited by-同舟云学术

Detection and Structural Characterization of Glutathione-Trapped Reactive Metabolites Using Liquid Chromatography−High-Resolution Mass Spectrometry and Mass Defect Filtering

Published:2007-10-06 Issue:21 Volume:79 Page:8333-8341
ISSN:0003-2700
Container-title:Analytical Chemistry
language:en
Short-container-title:Anal. Chem.

Author:

Zhu Mingshe¹,Ma Li¹,Zhang Haiying¹,Humphreys W. Griffith¹

Affiliation:

1. Department of Biotransformation, Pharmaceutical Candidate Optimization, Bristol-Myers Squibb Research and Development, Princeton, New Jersey 08543

Publisher

American Chemical Society (ACS)

Subject

Analytical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/ac071119u

Reference40 articles.

1. Screening for the potential of a drug candidate to cause idiosyncratic drug reactions

2. Drug−Protein Adducts: An Industry Perspective on Minimizing the Potential for Drug Bioactivation in Drug Discovery and Development

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