Analysis of Solvent Nucleophile Isotope Effects: Evidence for Concerted Mechanisms and Nucleophilic Activation by Metal Coordination in Nonenzymatic and Ribozyme-Catalyzed Phosphodiester Hydrolysis
Author:
Affiliation:
1. Center for RNA Molecular Biology and Department of Biochemistry, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106
Publisher
American Chemical Society (ACS)
Subject
Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/bi049188f
Reference88 articles.
1. Kinetic and magnetic resonance studies of effects of genetic substitution of a calcium-liganding amino acid in staphylococcal nuclease
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