Parallel Solid-Phase Synthesis and Evaluation of Inhibitors of Streptomyces coelicolor Type II Dehydroquinase-Reference-Cited by-同舟云学术

Parallel Solid-Phase Synthesis and Evaluation of Inhibitors of Streptomyces coelicolor Type II Dehydroquinase

Published:2003-11-22 Issue:26 Volume:46 Page:5735-5744
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

González-Bello Concepción¹,Lence Emilio¹,Toscano Miguel D.¹,Castedo Luis¹,Coggins John R.¹,Abell Chris¹

Affiliation:

1. Departamento de Química Orgánica y Unidad Asociada al C.S.I.C., Facultad de Química, Universidad de Santiago de Compostela, 15782 Santiago de Compostela, Spain, University Chemical Laboratory, Lensfield Road, Cambridge CB2 1EW, UK, and Biochemistry and Molecular Biology, University of Glasgow, Glasgow G12 8QQ, UK

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm030987q

Reference24 articles.

1. Abell, C.Enzymology and Molecular Biology of the Shikimate Pathway.InComprehensive Natural Products Chemistry, ed. Sankawa, U., Pergamon, Elsevier Science Ltd. Oxford, 1999; p 573.

2. Evidence for the shikimate pathway in apicomplexan parasites

3. 5-Enolpyruvylshikimate-3-phosphate synthase of Klebsiella pneumoniae. 2. Inhibition by glyphosate [N-(phosphononmethyl)glycine]

4. The herbicide glyphosate is a potent inhibitor of 5-enolpyruvylshikimic acid-3-phosphate synthase

5. Identification of the active-site lysine residues of two biosynthetic 3-dehydroquinases

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