Involvement of Metals in Enzymatic and Nonenzymatic Decomposition of C-Terminal α-Hydroxyglycine to Amide: An Implication for the Catalytic Role of Enzyme-Bound Zinc in the Peptidylamidoglycolate Lyase Reaction-Reference-Cited by-同舟云学术

Involvement of Metals in Enzymatic and Nonenzymatic Decomposition of C-Terminal α-Hydroxyglycine to Amide: An Implication for the Catalytic Role of Enzyme-Bound Zinc in the Peptidylamidoglycolate Lyase Reaction

Published:2009-01-26 Issue:7 Volume:48 Page:1654-1662
ISSN:0006-2960
Container-title:Biochemistry
language:en
Short-container-title:Biochemistry

Author:

Takahashi Kenichi¹,Harada Saori¹,Higashimoto Yuichiro¹,Shimokawa Chizu¹,Sato Hideaki¹,Sugishima Masakazu¹,Kaida Yasuhiko¹,Noguchi Masato¹

Affiliation:

1. Department of Medical Biochemistry, Kurume University School of Medicine, Kurume 830-0011, Japan, and Biomass Technology Research Center, National Institute of Advanced Industrial Science and Technology, Tosu 841-0052, Japan

Publisher

American Chemical Society (ACS)

Subject

Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/bi8018866

Reference40 articles.

1. New insights into copper monooxygenases and peptide amidation: structure, mechanism and function

2. Identification in pituitary tissue of a peptide alpha-amidation activity that acts on glycine-extended peptides and requires molecular oxygen, copper, and ascorbic acid.

3. Incorporation of aerobic oxygen into the hydroxyglycyl intermediate during formation of C-terminal peptide amides by peptidylglycine α-amidating monooxygenase (PAM)

4. The source of the oxygen atom in the α-hydroxyglycine intermediate of the peptidylglycine α-amidating reaction

5. Oxygen-18 isotopic carbon-13 NMR shift as proof that bifunctional peptidylglycine .alpha.-amidating enzyme is a monooxygenase

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2. Peptidylglycine monooxygenase activity of monomeric species of growth hormone;Heliyon;2019-09

3. Inactivation of peptidylglycine α-hydroxylating monooxygenase by cinnamic acid analogs;Journal of Enzyme Inhibition and Medicinal Chemistry;2015-05-29

4. α-Oxo Aldehyde or Glyoxylyl Group Chemistry in Peptide Bioconjugation;Bioconjugate Chemistry;2013-04-11

5. Probing the Production of Amidated Peptides following Genetic and Dietary Copper Manipulations;PLoS ONE;2011-12-16