Class III Antiarrhythmic Activity in Vivo by Selective Blockade of the Slowly Activating Cardiac Delayed Rectifier Potassium Current IKs by (R)-2-(2,4- Trifluoromethyl)-N-[2-oxo-5-phenyl- 1-(2,2,2-trifluoroethyl)-2,3-dihydro- 1H-benzo[e][1,4]diazepin-3-yl]acetamide-Reference-Cited by-同舟云学术

Class III Antiarrhythmic Activity in Vivo by Selective Blockade of the Slowly Activating Cardiac Delayed Rectifier Potassium Current IKs by (R)-2-(2,4- Trifluoromethyl)-N-[2-oxo-5-phenyl- 1-(2,2,2-trifluoroethyl)-2,3-dihydro- 1H-benzo[e][1,4]diazepin-3-yl]acetamide

Published:1997-11-01 Issue:24 Volume:40 Page:3865-3868
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Selnick Harold G.¹,Liverton Nigel J.¹,Baldwin John J.¹,Butcher John W.¹,Claremon David A.¹,Elliott Jason M.¹,Freidinger Roger M.¹,King Stella A.¹,Libby Brian E.¹,McIntyre Charles J.¹,Pribush David A.¹,Remy David C.¹,Smith Garry R.¹,Tebben Andrew J.¹,Jurkiewicz Nancy K.¹,Lynch Joseph J.¹,Salata Joseph J.¹,Sanguinetti Michael C.¹,Siegl Peter K. S.¹,Slaughter Donald E.¹,Vyas Kamlesh¹

Affiliation:

1. Departments of Medicinal Chemistry, Pharmacology, and Drug Metabolism, Merck Research Laboratories, West Point, Pennsylvania 19486

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm970517u

Reference28 articles.

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