A Bridging Water Anchors the Tethered 5-(3-Aminopropyl)-2′-deoxyuridine Amine in the DNA Major Groove Proximate to the N+2 C·G Base Pair: Implications for Formation of Interstrand 5′-GNC-3′ Cross-Links by Nitrogen Mustards,-Reference-Cited by-同舟云学术

A Bridging Water Anchors the Tethered 5-(3-Aminopropyl)-2′-deoxyuridine Amine in the DNA Major Groove Proximate to the N+2 C·G Base Pair: Implications for Formation of Interstrand 5′-GNC-3′ Cross-Links by Nitrogen Mustards,

Published:2008-06-13 Issue:27 Volume:47 Page:7147-7157
ISSN:0006-2960
Container-title:Biochemistry
language:en
Short-container-title:Biochemistry

Author:

Wang Feng¹,Li Feng¹,Ganguly Manjori¹,Marky Luis A.¹,Gold Barry¹,Egli Martin¹,Stone Michael P.¹

Affiliation:

1. Department of Chemistry, Center for Structural Biology, Center in Molecular Toxicology, and Vanderbilt-Ingram Cancer Center, Vanderbilt University, Nashville, Tennessee 37235, Department of Biochemistry, Center for Structural Biology, Center in Molecular Toxicology, School of Medicine, Vanderbilt University, Nashville, Tennessee 37232, Eppley Institute for Research in Cancer, University of Nebraska Medical Center, Omaha, Nebraska 68198-6805, Department of Pharmaceutical Sciences, University of Nebraska...

Publisher

American Chemical Society (ACS)

Subject

Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/bi800375m

Reference63 articles.

1. The reaction of mono- and di-functional alkylating agents with nucleic acids

2. Mechlorethamine cross-links deoxyguanosine residues at 5'-GNC sequences in duplex DNA fragments

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