Conformational Morphing by a DNA Analogue Featuring 7-Deazapurines and 5-Halogenpyrimidines and the Origins of Adenine-Tract Geometry-Reference-Cited by-同舟云学术

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Conformational Morphing by a DNA Analogue Featuring 7-Deazapurines and 5-Halogenpyrimidines and the Origins of Adenine-Tract Geometry

Published:2023-09-11 Issue:19 Volume:62 Page:2854-2867
ISSN:0006-2960
Container-title:Biochemistry
language:en
Short-container-title:Biochemistry

Author:

Pallan Pradeep S.¹,Lybrand Terry P.²,Rozners Eriks³^ORCID,Abramov Mikhail⁴,Schepers Guy⁴,Eremeeva Elena⁴,Herdewijn Piet⁴^ORCID,Egli Martin¹^ORCID

Affiliation:

1. School of Medicine, Department of Biochemistry, and Center for Structural Biology, Vanderbilt University, Nashville, Tennessee 37232, United States

2. Department of Chemistry and Center for Structural Biology, Vanderbilt University, Nashville, Tennessee 37232, United States

3. Department of Chemistry, Binghamton University, Binghamton, New York 13902, United States

4. Laboratory of Medicinal Chemistry, KU Leuven, Rega Institute for Medical Research, Minderbroedersstraat 10, Leuven 3000, Belgium

Funder

National Institute of General Medical Sciences

Publisher

American Chemical Society (ACS)

Subject

Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.biochem.3c00327

Reference92 articles.

1. Chemistry, structure and function of approved oligonucleotide therapeutics

2. RNA-Targeted Therapeutics

3. Aptamers as targeted therapeutics: current potential and challenges

4. Designing Chemically Modified Oligonucleotides for Targeted Gene Silencing

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