Potent and Highly Selective Benzimidazole Inhibitors of PI3-Kinase Delta-Reference-Cited by-同舟云学术

Potent and Highly Selective Benzimidazole Inhibitors of PI3-Kinase Delta

Published:2012-08-21 Issue:17 Volume:55 Page:7686-7695
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Murray Jeremy M.¹,Sweeney Zachary K.¹,Chan Bryan K.¹,Balazs Mercedesz¹,Bradley Erin¹,Castanedo Georgette¹,Chabot Christine¹,Chantry David¹,Flagella Michael¹,Goldstein David M.²,Kondru Rama²,Lesnick John¹,Li Jun¹,Lucas Matthew C.²,Nonomiya Jim¹,Pang Jodie¹,Price Stephen³,Salphati Laurent¹,Safina Brian¹,Savy Pascal P. A.³,Seward Eileen M.³,Ultsch Mark¹,Sutherlin Daniel P.¹

Affiliation:

1. Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, United States

2. Roche Research Center, 340 Kingsland Street, Nutley, New Jersey 07110, United States

3. Argenta Discovery, 8/9 Spire Green Centre, Flex Meadow, Harlow CM19 5TR, United Kingdom

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm300717c

Reference21 articles.

1. PI3K-signalling in B- and T-cells: insights from gene-targeted mice