Hypoxia-Activated Prodrugs: Substituent Effects on the Properties of Nitro seco-1,2,9,9a-Tetrahydrocyclopropa[c]benz[e]indol-4-one (nitroCBI) Prodrugs of DNA Minor Groove Alkylating Agents-Reference-Cited by-同舟云学术

Hypoxia-Activated Prodrugs: Substituent Effects on the Properties of Nitro seco-1,2,9,9a-Tetrahydrocyclopropa[c]benz[e]indol-4-one (nitroCBI) Prodrugs of DNA Minor Groove Alkylating Agents

Published:2009-10-30 Issue:22 Volume:52 Page:7258-7272
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Tercel Moana¹,Atwell Graham J.¹,Yang Shangjin¹,Stevenson Ralph J.¹,Botting K. Jane¹,Boyd Maruta¹,Smith Eileen¹,Anderson Robert F.¹²,Denny William A.¹,Wilson William R.¹,Pruijn Frederik B.¹

Affiliation:

1. Auckland Cancer Society Research Centre, Faculty of Medical and Health Sciences, The University of Auckland, Private Bag 92019, Auckland 1142, New Zealand

2. Department of Chemistry, The University of Auckland, Private Bag 92019, Auckland 1142, New Zealand

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm901202b

Reference43 articles.

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5. Design of anticancer prodrugs for reductive activation

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