Development of Dual-Acting Benzofurans for Thromboxane A2 Receptor Antagonist and Prostacyclin Receptor Agonist: Synthesis, Structure−Activity Relationship, and Evaluation of Benzofuran Derivatives-Reference-Cited by-同舟云学术

Development of Dual-Acting Benzofurans for Thromboxane A2 Receptor Antagonist and Prostacyclin Receptor Agonist: Synthesis, Structure−Activity Relationship, and Evaluation of Benzofuran Derivatives

Published:2005-07-15 Issue:16 Volume:48 Page:5279-5294
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Ohno Michihiro¹,Miyamoto Mitsuko¹,Hoshi Kazuhiro¹,Takeda Takahiro¹,Yamada Naohiro¹,Ohtake Atsushi¹

Affiliation:

1. Pharmaceutical Research Laboratories, Toray Industries, Inc., 1,111 Tebiro, Kamakura, Kanagawa, 248-8555, Japan

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm050194z

Reference21 articles.

1. Thromboxanes: a new group of biologically active compounds derived from prostaglandin endoperoxides.

2. Prevention of restenosis after percutaneous transluminal coronary angioplasty with thromboxane A2-receptor blockade. A randomized, double-blind, placebo-controlled trial. Coronary Artery Restenosis Prevention on Repeated Thromboxane-Antagonism Study (CARPORT).

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