Identification and Biological Evaluation of a Series of 1H-Benzo[de]isoquinoline-1,3(2H)-diones as Hepatitis C Virus NS5B Polymerase Inhibitors-Reference-Cited by-同舟云学术

Identification and Biological Evaluation of a Series of 1H-Benzo[de]isoquinoline-1,3(2H)-diones as Hepatitis C Virus NS5B Polymerase Inhibitors

Published:2009-07-24 Issue:16 Volume:52 Page:5217-5227
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Ontoria Jesus M.¹,Rydberg Edwin H.¹,Di Marco Stefania¹,Tomei Licia¹,Attenni Barbara¹,Malancona Savina¹,Martin Hernando José I.¹,Gennari Nadia¹,Koch Uwe¹,Narjes Frank¹,Rowley Michael¹,Summa Vincenzo¹,Carroll Steve S.²,Olsen David B.²,De Francesco Raffaele¹,Altamura Sergio¹,Migliaccio Giovanni¹,Carfì Andrea¹

Affiliation:

1. Istituto Di Ricerche Di Biologia Molecolare, P. Angeletti, S.p.A. (IRBM-MRL Rome), Via Pontina Km 30,600, I-00040 Pomezia, Italy

2. Antiviral Research, Merck Research Laboratories, West Point, Pennsylvania 19846

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm900517t

Reference40 articles.

1. WHO, January 2006, posting date.

2. Mechanism of action of interferon and ribavirin in treatment of hepatitis C