4-Oxo-1,4-dihydropyridines as Selective CB2 Cannabinoid Receptor Ligands: Structural Insights into the Design of a Novel Inverse Agonist Series-Reference-Cited by-同舟云学术

4-Oxo-1,4-dihydropyridines as Selective CB2 Cannabinoid Receptor Ligands: Structural Insights into the Design of a Novel Inverse Agonist Series

Published:2010-10-27 Issue:22 Volume:53 Page:7918-7931
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

El Bakali Jamal¹,Muccioli Giulio G.²,Renault Nicolas³,Pradal Delphine¹,Body-Malapel Mathilde⁴,Djouina Madjid⁴,Hamtiaux Laurie²,Andrzejak Virginie¹,Desreumaux Pierre⁴,Chavatte Philippe³,Lambert Didier M.²,Millet Régis¹

Affiliation:

1. Université Lille-Nord de France, Institut de Chimie Pharmaceutique Albert Lespagnol, EA 2692, IFR 114, 3 Rue du Professeur Laguesse, BP 83, 59006 Lille Cedex, France

2. Unité de Chimie Pharmaceutique et de Radiopharmacie, Louvain Drug Research Institute, Université Catholique de Louvain, 73 Avenue E. Mounier UCL-CMFA (7340), B-1200 Bruxelles, Belgium

3. Université Lille-Nord de France, Faculté de Pharmacie, Laboratoire de Chimie Thérapeutique, EA 1643, IFR 114, 3 Rue du Professeur Laguesse, BP 83, 59006 Lille Cedex, France

4. Physiopathologie des Maladies Inflammatoires de l’Intestin, Université Lille-Nord de France, Amphi J & K, U795, IFR 114, Boulevard du Professeur Leclercq, 59045 Lille Cedex, France

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm100286k

Reference67 articles.

1. The endocannabinoid system: a general view and latest additions

2. International Union of Pharmacology. XXVII. Classification of Cannabinoid Receptors

3. The Endocannabinoid System: Drug Targets, Lead Compounds, and Potential Therapeutic Applications

4. The Endocannabinoid System as an Emerging Target of Pharmacotherapy

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