Synthesis and Structure–Activity Relationship Study of Antimicrotubule Agents Phenylahistin Derivatives with a Didehydropiperazine-2,5-dione Structure-Reference-Cited by-同舟云学术

Synthesis and Structure–Activity Relationship Study of Antimicrotubule Agents Phenylahistin Derivatives with a Didehydropiperazine-2,5-dione Structure

Published:2012-01-20 Issue:3 Volume:55 Page:1056-1071
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Yamazaki Yuri¹²,Tanaka Koji²,Nicholson Benjamin³,Deyanat-Yazdi Gordafaried³,Potts Barbara³,Yoshida Tomoko²,Oda Akiko²,Kitagawa Takayoshi²,Orikasa Sumie²,Kiso Yoshiaki²,Yasui Hiroyuki⁴,Akamatsu Miki⁵,Chinen Takumi⁶,Usui Takeo⁶,Shinozaki Yuki¹,Yakushiji Fumika¹,Miller Brian R.³,Neuteboom Saskia³,Palladino Michael³,Kanoh Kaneo⁷,Lloyd George Kenneth³,Hayashi Yoshio¹²

Affiliation:

1. Department of Medicinal Chemistry, Tokyo University of Pharmacy and Life Sciences, Hachioji, Tokyo 192-0392, Japan

2. Department of Medicinal Chemistry, Center for Frontier Research in Medicinal Science, Kyoto Pharmaceutical University, Kyoto 607-8412, Japan

3. Nereus Pharmaceuticals, San Diego, California 92121, United States

4. Department of Analytical and Bioinorganic Chemistry, Kyoto Pharmaceutical University, Kyoto 607-8414, Japan

5. Laboratory of Comparative Agricultural Science, Division of Environmental Science and Technology, Graduate School of Agriculture, Kyoto University, Sakyo-ku, Kyoto 606-8502, Japan

6. Graduate School of Life and Environmental Sciences, University of Tsukuba, Tsukuba, Ibaraki 305-8572, Japan

7. Marine Biotechnology Institute Co., Ltd., Kamaishi, Iwate 026-0001, Japan

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm2009088

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