Pharmacophore Modeling and Virtual Screening for Novel Acidic Inhibitors of Microsomal Prostaglandin E2 Synthase-1 (mPGES-1)-Reference-Cited by-同舟云学术

Pharmacophore Modeling and Virtual Screening for Novel Acidic Inhibitors of Microsomal Prostaglandin E2 Synthase-1 (mPGES-1)

Published:2011-04-20 Issue:9 Volume:54 Page:3163-3174
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Waltenberger Birgit¹,Wiechmann Katja²,Bauer Julia²,Markt Patrick³,Noha Stefan M.³,Wolber Gerhard³⁴,Rollinger Judith M.¹,Werz Oliver²⁵,Schuster Daniela³,Stuppner Hermann¹

Affiliation:

1. Institute of Pharmacy, Pharmacognosy and Center for Molecular Biosciences Innsbruck (CMBI), University of Innsbruck, Innrain 52c, A-6020 Innsbruck, Austria

2. Department of Pharmaceutical Analytics, Pharmaceutical Institute, Eberhard Karls University Tuebingen, Auf der Morgenstelle 8, D-72076 Tuebingen, Germany

3. Institute of Pharmacy, Pharmaceutical Chemistry and Center for Molecular Biosciences Innsbruck (CMBI), University of Innsbruck, Innrain 52c, A-6020 Innsbruck, Austria

4. Institute of Pharmacy, Department of Pharmaceutical Chemistry, Freie Universität Berlin, Königin Luise-Strasse 2 + 4, D-14195 Berlin, Germany

5. Chair of Pharmaceutical/Medicinal Chemistry, Institute of Pharmacy, University of Jena, Philosophenweg 14, D-07743 Jena, Germany

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm101309g

Reference30 articles.

1. Biochemie und Pathobiochemie

2. Membrane Prostaglandin E Synthase-1: A Novel Therapeutic Target

3. Microsomal prostaglandin E2 synthase-1 in breast cancer: a potential target for therapy

4. Microsomal Prostaglandin E2 Synthase-1 (mPGES-1): A Novel Anti-Inflammatory Therapeutic Target

5. Coordinate up- and down-regulation of glutathione-dependent prostaglandin E synthase and cyclooxygenase-2 in A549 cells

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