Microsomal Prostaglandin E2 Synthase-1 (mPGES-1): A Novel Anti-Inflammatory Therapeutic Target-Reference-Cited by-同舟云学术

Microsomal Prostaglandin E2 Synthase-1 (mPGES-1): A Novel Anti-Inflammatory Therapeutic Target

Published:2008-05-07 Issue:14 Volume:51 Page:4059-4067
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Friesen Richard W.¹,Mancini Joseph A.¹

Affiliation:

1. Departments of Medicinal Chemistry and Biochemistry, Merck Frosst Centre for Therapeutic Research, 16711 Trans Canada Highway, Kirkland, Quebec H9H 3L1, Canada

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm800197b

Reference63 articles.

1. Altered pain perception and inflammatory response in mice lacking prostacyclin receptor

2. Intrinsic prostacyclin contributes to exudation induced by bradykinin or carrageenin: A study on the paw edema induced in IP-Receptor-deficient mice

3. Identification of human prostaglandin E synthase: A microsomal, glutathione-dependent, inducible enzyme, constituting a potential novel drug target

4. Purification and characterization of membrane-bound prostaglandin E synthase from bovine heart

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