IspG Converts an Epoxide Substrate Analogue to (E)-4-Hydroxy-3-methylbut-2-enyl Diphosphate: Implications for IspG Catalysis in Isoprenoid Biosynthesis
Author:
Affiliation:
1. Department of Pharmacology and Molecular Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, and Department of Chemistry, Boston University, Boston, Massachusetts 02215
Publisher
American Chemical Society (ACS)
Subject
Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis
Link
https://pubs.acs.org/doi/pdf/10.1021/ja907470n
Reference15 articles.
1. Biosynthesis of isoprenoids via the non-mevalonate pathway
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3. Accumulation of 2-C-methyl-d-erythritol 2,4-cyclodiphosphate in illuminated plant leaves at supraoptimal temperatures reveals a bottleneck of the prokaryotic methylerythritol 4-phosphate pathway of isoprenoid biosynthesis
4. The non-mevalonate pathway of isoprenoids: genes, enzymes and intermediates
5. Revisiting the IspH Catalytic System in the Deoxyxylulose Phosphate Pathway: Achieving High Activity
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