1. College of Pharmacy, University of Michigan, 428 Church Street, Ann Arbor, Michigan 48109-1065, Department of Biological Chemistry, Medical School, University of Michigan, 3301B MSRB III, Ann Arbor, Michigan 48109-0606, Discovery Technologies, Pfizer Global Research and Development, Ann Arbor, Michigan 48105, Interdisciplinary Research Center, Giessen University, Heinrich Buff-Ring 26-32, D-35392 Giessen, Germany, Wellcome Trust Biocentre, University of Dundee, Dundee DD1 5EH, U.K., and Biochemie-Zentrum...