Structural Basis for the Preference of UTP over ATP in Human Deoxycytidine Kinase: Illuminating the Role of Main-Chain Reorganization-Reference-Cited by-同舟云学术

Structural Basis for the Preference of UTP over ATP in Human Deoxycytidine Kinase: Illuminating the Role of Main-Chain Reorganization

Published:2005-12-06 Issue:2 Volume:45 Page:452-461
ISSN:0006-2960
Container-title:Biochemistry
language:en
Short-container-title:Biochemistry

Author:

Godsey Michael H.¹,Ort Stephan¹,Sabini Elisabetta¹,Konrad Manfred¹,Lavie Arnon¹

Affiliation:

1. Department of Biochemistry and Molecular Genetics, University of Illinois at Chicago, 900 South Ashland Avenue, Chicago, Illinois 60607, and Department of Molecular Genetics, Max Planck Institute for Biophysical Chemistry, Am Fassberg 11, D-37077 Göttingen, Germany

Publisher

American Chemical Society (ACS)

Subject

Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/bi0518646

Reference42 articles.

1. Expression of deoxycytidine kinase and phosphorylation of 2-chlorodeoxyadenosine in human normal and tumour cells and tissues

2. In vitro-induced resistance to the deoxycytidine analogues cytarabine (AraC) and 5-aza-2′-deoxycytidine (DAC) in a rat model for acute myeloid leukemia is mediated by mutations in the deoxycytidine kinase (dck) gene

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