(1S, 3S)-3-Amino-4-difluoromethylenyl-1-cyclopentanoic Acid (CPP-115), a Potent γ-Aminobutyric Acid Aminotransferase Inactivator for the Treatment of Cocaine Addiction

Author:

Pan Yue1,Gerasimov Madina R.2,Kvist Trine,Wellendorph Petrine,Madsen Karsten K.,Pera Elena3,Lee Hyunbeom1,Schousboe Arne,Chebib Mary3,Bräuner-Osborne Hans,Craft Cheryl M.4,Brodie Jonathan D.5,Schiffer Wynne K.2,Dewey Stephen L.2,Miller Steven R.6,Silverman Richard B.1

Affiliation:

1. Department of Chemistry and Department of Molecular Biosciences, Chemistry of Life Processes Institute, Center for Molecular Innovation and Drug Discovery, Northwestern University, Evanston, Illinois 60208-3113, United States

2. Center for Neurosciences, Feinstein Institute for Medical Research, North Shore-LIJ Health System, Manhasset, New York 11030, United States

3. Faculty of Pharmacy, The University of Sydney, Sydney, NSW 2006, Australia

4. Department of Ophthalmology and Cell & Neurobiology, Mary D. Allen Laboratory for Vision Research, Doheny Eye Institute, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, United States

5. Department of Psychiatry, New York University School of Medicine, New York, New York 10016, United States

6. Catalyst Pharmaceutical Partners, Inc., Coral Gables, Florida 33134, United States

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

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