Exploiting the Proton Exchange as an Additional Route to Enhance the Relaxivity of Paramagnetic MRI Contrast Agents

Author:

Aime Silvio1,Baroni Simona1,Delli Castelli Daniela1,Brücher Ernő,Fábián IstvánORCID,Serra Sonia Colombo2,Fringuello Mingo Alberto2,Napolitano Roberta2,Lattuada Luciano2,Tedoldi Fabio2,Baranyai Zsolt2ORCID

Affiliation:

1. Department of Molecular Biotechnologies and Health Sciences, Molecular Imaging Center, University of Torino, Via Nizza 52, 10126 Torino, Italy

2. Bracco Imaging Spa, Bracco Research Centre, Via Ribes 5, 10010 Colleretto Giacosa (TO), Italy

Funder

Orsz?gos Tudom?nyos Kutat?si Alapprogramok

Regione Piemonte

Publisher

American Chemical Society (ACS)

Subject

Inorganic Chemistry,Physical and Theoretical Chemistry

Reference36 articles.

1. Relaxivity of Gadolinium(III) Complexes: Theory and Mechanism

2. Classification and basic properties of contrast agents for magnetic resonance imaging

3. Gadolinium(III) Chelates as MRI Contrast Agents:  Structure, Dynamics, and Applications

4. Lanthanide induced shifts and relaxation rate enhancements

5. Helm, L.; Morrow, J. R.; Bond, C. J.; Carniato, F.; Botta, M.; Braun, M.; Baranyai, Z.; Pujales-Paradela, R.; Regueiro-Figueroa, M.; Esteban-Gomez, D.; Platas-Iglesias, C.; Scholl, T. J. In Contrast Agents for MRI: Experimental Methods; Pierre, V. C., Allen, M. J., Eds. The Royal Society of Chemistry, 2018; p 121.

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