Unlocking Cu(I)-Mediated Catalytic Pathways for Efficient ROS Generation by Incorporating an Oxazole-Based Histidine Surrogate into Cu(II)

Unlocking Cu(I)-Mediated Catalytic Pathways for Efficient ROS Generation by Incorporating an Oxazole-Based Histidine Surrogate into Cu(II)–ATCUN Complexes

Published:2023-06-21 Issue:26 Volume:62 Page:10279-10290
ISSN:0020-1669
Container-title:Inorganic Chemistry
language:en
Short-container-title:Inorg. Chem.

Author:

Lee Yen Jea¹^ORCID,Kim Yujeong²^ORCID,Kim Haesol³,Choi Jieun¹,Noh Ga Hee⁴,Lee Kug-Seung⁵^ORCID,Lee Junseong⁴^ORCID,Choi Chang Hyuck³⁶^ORCID,Kim Sun Hee²⁷^ORCID,Seo Jiwon¹^ORCID

Affiliation:

1. Department of Chemistry, Gwangju Institute of Science and Technology, Gwangju 61005, Republic of Korea

2. Western Seoul Center, Korea Basic Science Institute, Seoul 03759, Republic of Korea

3. Department of Chemistry, Pohang University of Science and Technology, Pohang 37673, Republic of Korea

4. Department of Chemistry, Chonnam National University, Gwangju 61186, Republic of Korea

5. Beamline Department, Pohang Accelerator Laboratory, Pohang University of Science and Technology, Pohang 37673, Republic of Korea

6. Institute for Convergence Research and Education in Advanced Technology (I−CREATE), Yonsei University, Seoul 03722, Republic of Korea

7. Department of Chemistry, Chung-Ang University, Seoul 06974, Republic of Korea

Funder

National Research Foundation of Korea

Gwangju Institute of Science and Technology

Publisher

American Chemical Society (ACS)

Subject

Inorganic Chemistry,Physical and Theoretical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.inorgchem.3c01084

Reference67 articles.

1. Amino Terminal Cu(II)- and Ni(II)-Binding (ATCUN) Motif of Proteins and Peptides: Metal Binding, DNA Cleavage, and Other Properties

2. Circulatory zinc transport is controlled by distinct interdomain sites on mammalian albumins

3. Kinetics and thermodynamics of metal binding to the N-terminus of a human copper transporter, hCTR1

4. Sequence proximity between Cu(II) and Cu(I) binding sites of human copper transporter 1 model peptides defines reactivity with ascorbate and O2

5. Antimicrobial Metallopeptides

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